Gene mutation may be the reason for “drinking water and getting fat”
According to a study published in the journal Cell Metabolisma study, studies in mice showed that a mutation in a gene called Ovol2 causes obesity. Compared with their unmutated littermates, the obese mice had a 556 percent increase in fat mass and a 20 percent decrease in lean body mass. Experiments have shown that obese animals fail to maintain core body temperature when exposed to cold, which appears to be due to their inability to efficiently utilize a tissue called brown fat, whose main function is to generate heat. Further tests showed that the healthy Ovol2 gene suppressed the development of white fat, the main tissue responsible for energy storage.